Integrin Alpha V Beta 3 antibody LS-C524461 is a biotin-conjugated mouse monoclonal antibody to Integrin Alpha V Beta 3 from human and chicken. Validated for Flow, IHC and IP.
Human Integrin Alpha V Beta 3
(tested or 100% immunogen sequence identity)
Osteoclasts from osteoclastomas
Recognizes the intact complex formed between the CD51 and CD61 molecules (alpha V and beta 3 integrins). This complex binds vitronectin at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets. Species cross-reactivity: Human and chicken. Does not cross-react with porcine, lapine or bovine tissue.