Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
- IHC - Paraffin (0.5 - 1 µg/ml)
- Western blot (0.5 - 1 µg/ml)
See our complete line of Immunohistochemistry Reagents
including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
INSL3 antibody was raised against synthetic peptide from the C-terminus of human INSL3 (CCLSGCTQQDLLTLCPY, aa115-131 of UniProt P51460). Percent identity by BLAST analysis: Human (100%); Sheep, Bovine, Bat, Goat, Horse, Pig (88%); Mouse, Rat, Ferret, Cat, Hamster, Elephant, Dog (82%).
Insulin-like 3 (INSL3), a member of the insulin-like hormone superfamily, is specifically expressed in Leydig cells of the fetal and postnatal testis and in theca cells of the postnatal ovary. It is synthesized as a 131-amino acid preproprotein, which contains a 24-amino acid signal peptide. The human INSL3 gene is assigned to bands p13.2-p12 of the short arm of chromosome 19 with the similar organization to that of insulin and relaxin. INSL3 induces gubernaculum development in an androgen-independent way, while androgen-mediated regression of the CSL occurs independently from Insl3. Moreover, INSL3 is a ligand for LGR8 and INSL3-LGR8 mutations are believed to be associated with human cryptorchidism.
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
0.2 ml Sterile distilled water
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
For research use only.
This antibody carries the LSBio 100% Guarantee.