Influenza Virus Influenza A Virus H5
(tested or 100% immunogen sequence identity)
Purified Avian Influenza Virus Type A (H5N1).
Detects hemagglutinin H5 from the Influenza A virus H5N1. Influenza A belongs to the Orthomyxoviridae family, and is a negative sense single-stranded RNA virus which results in respiratory disease. Hemagglutinin is an antigenic glycoprotein which allows viral attachment and entry into the cell. Sixteen subtypes of hemagglutinin (H1-H16) have been described, of which H1, H2 and H3 infect humans. H5 and H7 normally result in avian disease, with some highly pathogenic H5N1 strains causing 100% mortality in poultry. H5N1 has in some cases mutated to infect humans, with 60% mortality. Hemagglutinin is one of the most medically relevant antigens on influenza as it is a target for antiviral drugs and antibodies. May be used as a capture antibody in ELISA assays for Influenza H5N1.
ELISA: This product may be used in an indirect ELISA or as a capture antibody in a sandwich ELISA together with LS-C58232
as a detection reagent.
PBS, pH 7.4, 0.09% Sodium Azide
Short term: -20°C; Long term: -20°C.
For research use only.