Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Western blot (1:100 - 1:400)
(applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
IL12RB1 / CD212 antibody was raised against recombinant IL12Rb1 (Leu429-Asn603) expressed in E. coli.
The antibody is a rabbit polyclonal antibody raised against IL12Rb1. It has been selected for its ability to recognize IL12Rb1 in immunohistochemical staining and western blotting.
ELISA 1:100-1:5000; ICC 1:50-500; WB 1:50-400;
PBS, pH 7.4, 0.02% Sodium Azide, 50% Glycerol
Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months.
IL12RB1 / CD212 is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling.