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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL10RB Antibody LS‑C130245
IL10RB antibody LS-C130245 is an unconjugated rat monoclonal antibody to IL10RB from human and mouse. Validated for ELISA and Flow.
Antibody
Catalog
Size
Price
LS-C130245-100
100 µg
$620

Popular IL10RB Products

Antibody
Species: Human
Applications: Flow Cytometry
Immunohistochemistry of Human esophagus cancer using IL10RB Polyclonal Antibody at dilution of 1:20.
Species: Human
Applications: IHC, ELISA
Immunohistochemistry image at a dilution of 1:100 and staining in paraffin-embedded human glioma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Western blot of recombinant IL10RB / IL-10R2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse
Applications: IHC, Western blot

Product Description

IL10RB Antibody for ELISA, Flow LS-C130245

Specifications

Target
Human IL10RB
Synonyms
IL10RB, CDW210B, CDw210b antigen, D21S66, IL-10R subunit 2, IBD25, IL-10R2, Interleukin 10 receptor, beta, IL-10 receptor subunit beta, IL-10R subunit beta, IL-10RB, CRF2-4, CRFB4, D21S58
Host
Rat
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Flow Cytometry (25 µg/ml)
  • ELISA
Immunogen
IL10RB antibody was raised against recombinant corresponding to mouse IL-10R expressed in NSO cells (Q61190).
Specificity
Recognizes mouse IL-10 Rb. Species sequence homology: 87% rat and 74% human.
Usage
Suitable for use in ELISA and Flow Cytometry. ELISA: Direct in Recombinant mouse IL-10Rb. Flow Cytometry: 25 ug/ml.
Presentation
Lyophilized from PBS, 5% Trehalose
Reconstitution
200ul sterile PBS
Storage
Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.
Restrictions
For research use only.
About IL10RB
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Q08334 NM_000628 NP_000619.3


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Requested From: United States
Date Requested: 10/17/2018

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