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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IL‑1B / IL‑1 Beta Antibody LS‑C42757
IL-1 Beta antibody LS-C42757 is an unconjugated rabbit polyclonal antibody to sheep IL-1 Beta (IL-1B). Validated for ELISA and WB. Cited in 1 publication.
100 µl

Popular IL-1B / IL-1 Beta Products

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IL1B mouse monoclonal antibody.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species: Human
Applications: IHC, Immunoprecipitation, ELISA, Neutralization
Anti-Human IL-1B Antibody - Western Blot. IL-1B was used at a 1:200 dilution incubated 1 h at room temperature to detect dog IL-1B by Western blot. Lane 1 and 2 were loaded with 2.5 ug and 500 ng of dog IL-1B respectively. The molecular weight of the detected band is estimated by comparison to molecular weight markers (not shown). Detection occurred using a 1:3000 dilution of IRDye800 conjugated Donkey anti-Rabbit IgG (code # for 1h at room temperature. LICORs Odyssey Infrared Imaging System was used to scan and process the image. Other detection systems will yield similar results.
Species: Human, Dog, Primate
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, ELISA, Radioimmunoassay

Product Description

IL-1 Beta antibody LS-C42757 is an unconjugated rabbit polyclonal antibody to sheep IL-1 Beta (IL-1B). Validated for ELISA and WB. Cited in 1 publication.
About IL-1B / IL-1 Beta
IL-1 Beta is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. P01584 NM_000576 NP_000567.1

IL1B Antibody, IL-1B Antibody, IL-1 beta Antibody, IL1-BETA Antibody, Preinterleukin 1 beta Antibody, Pro-interleukin-1-beta Antibody, Catabolin Antibody, IL-1 Antibody, IL1F2 Antibody, Interleukin 1, beta Antibody, Interleukin-1 beta Antibody


Sheep IL-1B / IL-1 Beta
Sheep (tested or 100% immunogen sequence identity)
IgG Polyclonal
  • Western blot
  • ELISA (1:500)
Recombinant IL-1 beta.
Recognizes ovine interleukin-1 beta (IL-1 beta). No cross-reactivity is seen with ovine IL-6, IL-8, MCP-1 or TNF alpha. Neutralizes the bioactivity of ovine IL-1 beta. Removal of sodium azide is recommended prior to use in functional assays.
Serum, 0.1% Sodium Azide
Store at 4°C or -20°C. Avoid freeze-thaw cycles. Store undiluted.
For research use only.

Publications (1)

Ontogeny and the effects of in utero brain ischemia on interleukin-1 beta and interleukin-6 protein expression in ovine cerebral cortex and white matter. Sadowska GB, Threlkeld SW, Flangini A, Sharma S, Stonestreet BS. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2012 Oct;30:457-63. [Full Text Article] [PubMed:22698958] [PMC:PMC3438310]

Customer Reviews (0)

Requested From: United States
Date Requested: 9/23/2018

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