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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
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Catalog Number Size Price
LS-C388698-100 100 µg $435 
IL-1B / IL-1 Beta Antibody - Western blot testing of IL1 beta antibody and Lane 1: Recombinant mouse IL1b protein 10ng; 2: 5ng; 3: 2.5ng

Polyclonal IL‑1B / IL‑1 Beta Antibody (aa250‑265, WB) LS‑C388698

Polyclonal IL‑1B / IL‑1 Beta Antibody (aa250‑265, WB) LS‑C388698

Antibody:
Rabbit Polyclonal to Mouse IL-1B / IL-1 Beta
Application:
WB
Reactivity:
Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$435 
LS-C388698-100
100 µg
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Mouse IL-1B / IL-1 Beta
Application:
WB
Reactivity:
Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
IL-1 Beta antibody LS-C388698 is an unconjugated rabbit polyclonal antibody to IL-1 Beta (IL-1B ) from mouse and rat. Validated for WB.
Target
Mouse IL-1B / IL-1 Beta
Synonyms
IL1B | IL-1B | IL-1 beta | IL1-BETA | Preinterleukin 1 beta | Pro-interleukin-1-beta | Catabolin | IL-1 | IL1F2 | Interleukin 1, beta | Interleukin-1 beta
Host
Rabbit
Reactivity
Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.5 - 1 µg/ml)
Immunogen
Synthetic peptide from the C-Terminus of mouse IL1 beta (FLGNNSGQDIIDFTME, aa250-265 of UniProt P10749). Percent identity by BLAST analysis: Mouse (100%); Hamster, Rabbit (88%); Ferret, Elephant, Pig, Guinea pig, Dog (81%); Rat (75%); Human (69%).
Epitope
aa250-265
Specificity
Mouse IL-1B / IL-1 Beta
Usage
Interleukin-1 beta (IL-1beta) also know as catabolin, is a cytokine protein that in humans is encoded by the IL1B gene, which localizes to the long arm of chromosome at position 2q13-2q21 between two fragile sites. Interleukin 1 (IL-1) is a protein with several biological activities regulating host defense and immune responses.2 The human IL-1 family plays an important role in the pathogenesis of many diseases and functions as a key mediator of the host response to various infectious, inflammatory, and immunologic challenges.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About IL-1B / IL-1 Beta
P01584 NM_000576 NP_000567.1

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Requested From: United States
Date Requested: 2/25/2020