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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16336-0.1 | 0.1 ml (1 mg/ml) | $460 |
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PathPlus™ Monoclonal Mouse anti‑Human TFE3 Antibody (clone AHC0245, Ready‑to‑Use, IHC, WB) LS‑B16336
PathPlus™ Monoclonal Mouse anti‑Human TFE3 Antibody (clone AHC0245, Ready‑to‑Use, IHC, WB) LS‑B16336
Note: This antibody replaces LS-C683665
Antibody:
TFE3 Mouse anti-Human Monoclonal (Ready-to-Use) (AHC0245) Antibody
Application:
IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Ready-to-Use
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
TFE3 Mouse anti-Human Monoclonal (Ready-to-Use) (AHC0245) Antibody
Application:
IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Ready-to-Use
Specifications
Description
TFE3 (Transcription factor binding to IGHM enhancer 3) is a nuclear protein that promotes the expression of genes downstream to TGF-beta signaling. Chromosomal translocations between this gene (located on Xp11.2) and other genes promote growth and proliferation, and oncogenic activation. Translocation or overexpression of this gene has been implicated in renal cell carcinoma, lung adenocarcinoma, alveolar soft-part sarcoma, papillary thyroid carcinoma, melanoma, and mesotheliomas. It is expressed in a wide variety of tissues, and is nuclear in localization.
References: AmJSurgPathol 2009 33:1894; Histopath 1993, 23:439
Target
Human TFE3
Synonyms
TFE3 | BHLHe33 | Transcription factor E3 | RCCX1 | TFEA | RCCP2
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
AHC0245
Conjugations
Unconjugated
Purification
Affinity purified from ascites
Modifications
Ready-to-Use
Immunogen
Human TFE3
Specificity
Human TFE3
Applications
- IHC - Paraffin (10 µg/ml)
- Western blot (1:500 - 1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4 with 0.02% Sodium Azide
Storage
Store at 2-8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TFE3
Validation
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ TFE3 Antibody (clone AHC0245, Ready-to-Use) for IHC, WB/Western LS-B16336 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse, Rat, Bovine, Dog, Pig
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC - Paraffin, Western blot, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC - Paraffin, Western blot, ELISA
Species:
Human, Mouse, Rat, Bovine, Dog, Pig
Applications:
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/26/2024
Date Requested: 4/26/2024
