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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A3898-50 50 µg (1 mg/ml) $425 
PTGER4 / EP4 Antibody - Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PTGER4 / EP4 Antibody - Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
PTGER4 / EP4 Antibody - Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with PTGER4 / EP4.
PTGER4 / EP4 Antibody - Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PTGER4 / EP4 Antibody - Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
PTGER4 / EP4 Antibody - Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with PTGER4 / EP4.
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IHCPlus™ Polyclonal PTGER4 / EP4 Antibody (N‑Terminus, IHC) LS‑A3898

IHCPlus™ Polyclonal PTGER4 / EP4 Antibody (N‑Terminus, IHC) LS‑A3898

Antibody:
Rabbit Polyclonal to Human PTGER4 / EP4
Application:
IHC, IHC-P, ICC
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A3898-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human PTGER4 / EP4
Application:
IHC, IHC-P, ICC
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
EP4 antibody LS-A3898 is an unconjugated rabbit polyclonal antibody to human EP4 (PTGER4) (N-Terminus). Validated for ICC and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Target
Human PTGER4 / EP4
Synonyms
PTGER4 | EP4 | EP4 prostaglandin receptor | EP4R | PGE receptor EP4 subtype | Prostanoid EP4 receptor | Prostaglandin E receptor 4 | PGE receptor, EP4 subtype | PGE2 receptor EP4 subtype
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 - 20 µg/ml)
  • ICC
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 14 amino acid peptide from N-Terminus extracellular domain of human PTGER4 / EP4. Percent identity with other species by BLAST analysis: Human (100%); Chimpanzee, Gorilla, Marmoset (93%); Gibbon, Monkey (86%).
Epitope
N-Terminus
Specificity
Human PTGER4 / EP4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About PTGER4 / EP4
P35408 NM_000958 NP_000949.1

Validation

PTGER4 / EP4 Antibody - Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PTGER4 / EP4 Antibody - Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.

PTGER4 / EP4 Antibody - Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with PTGER4 / EP4.
Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with PTGER4 / EP4.
Anti-PTGER4 / EP4 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with PTGER4 / EP4.

LSBio Ratings

IHC-plus™ PTGER4 / EP4 Antibody (N-Terminus) for IHC, ICC LS-A3898 has an LSBio Rating of
Publications (4.1)
Laboratory Validation Score (4)

Publications (2)

Identification of EP4 as a potential target for the treatment of castration-resistant prostate cancer using a novel xenograft model. Terada N, Shimizu Y, Kamba T, Inoue T, Maeno A, Kobayashi T, Nakamura E, Kamoto T, Kanaji T, Maruyama T, Mikami Y, Toda Y, Matsuoka T, Okuno Y, Tsujimoto G, Narumiya S, Ogawa O. Cancer research. 2010 Feb;70:1606-15.

EP4 and Class III ß-Tubulin Expression in Uterine Smooth Muscle Tumors: Implications for Prognosis and Treatment. Reader J, Harper AK, Legesse T, Staats PN, Goloubeva O, Rao GG, Fulton A, Roque DM. Cancers. 2019 October;11:E1590.

Customer Reviews (0)


Requested From: United States
Date Requested: 3/30/2020