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| Catalog Number | Size | Price |
|---|---|---|
| LS-A7164-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human NEK7 Antibody (Kinase Domain, IHC) LS‑A7164
PathPlus™ Polyclonal Rabbit anti‑Human NEK7 Antibody (Kinase Domain, IHC) LS‑A7164
Antibody:
NEK7 Rabbit anti-Human Polyclonal (Kinase Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
NEK7 Rabbit anti-Human Polyclonal (Kinase Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
NEK7 is a protein kinase that plays an important role in mitotic cell cycle progression. It is required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis. NEK7 phosphorylates RPS6KB1. In cancer, it is upregulated in hepatocellular carcinoma and is thought to promote cancer cell proliferation.
References: Oncotarget. 2016 Apr 5; 7(14): 18620–18630, PMID: 26921196
Target
Human NEK7
Synonyms
NEK7 | NimA-related protein kinase 7 | NIMA-related kinase 7
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey, Bovine, Pig, Rabbit, Chicken, Xenopus (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 17 amino acid peptide from kinase domain of human NEK7. Percent identity with other species by BLAST analysis: Human, Gibbon, Marmoset (100%); Monkey, Elephant, Panda, Bovine, Rabbit, Pig, Opossum, Turkey, Chicken, Xenopus, Stickleback, Pufferfish (94%); Mouse, Rat, Hamster, Dog, Bat, Horse, Salmon, Zebrafish (88%).
Epitope
Kinase Domain
Specificity
Human NEK7. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
- IHC
- IHC - Paraffin (1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About NEK7
Validation
Colon carcinoma
Colon carcinoma
Ovary, carcinoma
Ovary, carcinoma
Prostate, Carcinoma
Prostate, Carcinoma
Anti-NEK7 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NEK7 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Colon, Carcinoma
Colon, Carcinoma
Anti-NEK7 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NEK7 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NEK7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NEK7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ NEK7 Antibody (Kinase Domain) for IHC LS-A7164 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/25/2024
Date Requested: 4/25/2024
