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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A476-50 50 µg (1 mg/ml) $425 
HRH3 / Histamine 3 Receptor Antibody - Anti-HRH3 / Histamine H3 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
HRH3 / Histamine 3 Receptor Antibody - Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with HRH3 / Histamine H3 Receptor.
HRH3 / Histamine 3 Receptor Antibody - Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
HRH3 / Histamine 3 Receptor Antibody - Anti-HRH3 / Histamine H3 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
HRH3 / Histamine 3 Receptor Antibody - Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with HRH3 / Histamine H3 Receptor.
HRH3 / Histamine 3 Receptor Antibody - Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
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IHCPlus™ Polyclonal Rabbit anti‑Human HRH3 / Histamine 3 Receptor Antibody (Cytoplasmic Domain, IHC) LS‑A476

IHCPlus™ Polyclonal Rabbit anti‑Human HRH3 / Histamine 3 Receptor Antibody (Cytoplasmic Domain, IHC) LS‑A476

Antibody:
Rabbit Polyclonal to Human HRH3 / Histamine 3 Receptor
Application:
IHC, IHC-P, ICC
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A476-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human HRH3 / Histamine 3 Receptor
Application:
IHC, IHC-P, ICC
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Histamine 3 Receptor antibody LS-A476 is an unconjugated rabbit polyclonal antibody to Histamine 3 Receptor (HRH3) (Cytoplasmic Domain) from human. It is reactive with human and monkey. Validated for ICC and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Target
Human HRH3 / Histamine 3 Receptor
Synonyms
HRH3 | G protein-coupled receptor 97 | GPCR97 | H3 histamine receptor | H3R | HH3R | Histamine H3 receptor | Histamine receptor H3 | G-protein coupled receptor 97 | Histamine 3 receptor
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (18 - 36 µg/ml)
  • ICC
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human HRH3 / Histamine H3 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Mouse, Rat, Hamster, Elephant, Bovine, Dog, Horse, Opossum, Guinea pig, Platypus (88%); Bat, Turkey (81%).
Blocking Peptide
LS-E28991 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A476. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Cytoplasmic Domain
Specificity
Human HRH3 / Histamine H3 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About HRH3 / Histamine 3 Receptor
Q9Y5N1 NM_007232 NP_009163.2

Validation

HRH3 / Histamine 3 Receptor Antibody - Anti-HRH3 / Histamine H3 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HRH3 / Histamine H3 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-HRH3 / Histamine H3 Receptor antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

HRH3 / Histamine 3 Receptor Antibody - Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with HRH3 / Histamine H3 Receptor.
Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with HRH3 / Histamine H3 Receptor.
Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with HRH3 / Histamine H3 Receptor.

HRH3 / Histamine 3 Receptor Antibody - Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.
Anti-HRH3 / Histamine H3 Receptor antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.

LSBio Ratings

IHC-plus™ HRH3 / Histamine 3 Receptor Antibody (Cytoplasmic Domain) for IHC, ICC LS-A476 has an LSBio Rating of
Publications (4)
Laboratory Validation Score (4)

Publications (1)

Activation of histamine H3 receptor decreased cytoplasmic Ca(2+) imaging during electrical stimulation in the skeletal myotubes. Paavola J, Stegajev V, Stark H, Chazot PL, Wen JG, Konttinen YT. European journal of pharmacology. Mar;754:173-178.

Customer Reviews (0)


Requested From: United States
Date Requested: 7/6/2020