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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-B5916-50 50 µg (0.5 mg/ml) $425 
DSG1 / Desmoglein 1 Antibody - Anti-DSG1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.

IHCPlus™ Polyclonal Goat anti‑Human DSG1 / Desmoglein 1 Antibody (aa841‑855, IHC) LS‑B5916

IHCPlus™ Polyclonal Goat anti‑Human DSG1 / Desmoglein 1 Antibody (aa841‑855, IHC) LS‑B5916

Note: This antibody replaces LS-C112869
Antibody:
Goat Polyclonal to Human DSG1 / Desmoglein 1
Application:
IHC, IHC-P, Peptide-ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$425 
LS-B5916-50
50 µg
0.5 mg/ml
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Goat Polyclonal to Human DSG1 / Desmoglein 1
Application:
IHC, IHC-P, Peptide-ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Desmoglein 1 antibody LS-B5916 is an unconjugated goat polyclonal antibody to human Desmoglein 1 (DSG1) (aa841-855). Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues.
Target
Human DSG1 / Desmoglein 1
Synonyms
DSG1 | CDHF4 | Cadherin family member 4 | Desmoglein 1 | DG1 | Desmoglein-1 | Desmosomal glycoprotein 1 | SPPK1 | DGI | DSG | Pemphigus foliaceus antigen | PPKS1
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (3.75 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Peptide with sequence C-YTTSDTLKPSVHVHD, from the internal region of the protein sequence according to NP_001933.2.
Blocking Peptide
LS-E27151 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B5916. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa841-855
Specificity
Human DSG1.
Usage
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments in lysates of cell lines A431, HeLa, K562 and MOLT4 gave no specific signal but low background (at antibody concentration up to 1 ug/ml).
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About DSG1 / Desmoglein 1
Q02413 NM_001942 NP_001933.2

Validation

DSG1 / Desmoglein 1 Antibody - Anti-DSG1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-DSG1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
Anti-DSG1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.

LSBio Ratings

IHC-plus™ DSG1 / Desmoglein 1 Antibody (aa841-855) for IHC LS-B5916 has an LSBio Rating of
Laboratory Validation Score (4)

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Requested From: United States
Date Requested: 7/11/2020