Human IFI16

Rabbit

Human (tested or 100% immunogen sequence identity)

Polyclonal

Unconjugated

Protein G purified

Unmodified

Recombinant protein encompassing the PAAD domain (aa 6-102) of human IFI16.

Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.

• Western blot (1:100 - 1:500)
• ELISA (1:500 - 1:1000)

PBS, pH 7.4, 0.09% Sodium Azide

Store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q16666 NCBI: NM_005531 NP_005522.2