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Catalog Number Size Price
LS-C499094-50 50 µg $294 
LS-C499094-100 100 µg $360 
Antibody

Polyclonal Rabbit anti‑Human IER3 / IEX‑1 Antibody (Biotin) LS‑C499094

Polyclonal Rabbit anti‑Human IER3 / IEX‑1 Antibody (Biotin) LS‑C499094

Antibody:
IER3 / IEX-1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:
Price
Catalog Number
$294
LS-C499094-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
IER3 / IEX-1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Application:
ELISA
Reactivity:
Human
Format:
Biotin, Unmodified
Other formats:

Specifications

Description
IEX-1 antibody LS-C499094 is a biotin-conjugated rabbit polyclonal antibody to human IEX-1 (IER3). Validated for ELISA.
Target
Human IER3 / IEX-1
Synonyms
IER3 | DIF-2 | DIF2 | Gly96, mouse, homolog of | IEX1 | IEX-1L | Immediate early protein GLY96 | Immediate early response 3 | Immediately early gene X-1 | GLY96 | IEX-1 | Protein DIF-2 | Protein PRG1 | PRG1 | Anti-death protein
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with HRP, FITC.
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Radiation-inducible immediate-early gene IEX-1 protein (1-82AA)
Specificity
May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
Applications
  • ELISA
  • Applications tested for the base form of this product only
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About IER3 / IEX-1
P46695 NM_003897 NP_003888.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 5/1/2024