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May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Gene Name: | leucine rich repeat (in FLII) interacting protein 2 |
Synonyms: | LRRFIP2, LRR FLII-interacting protein 2, HUFI-2 |
Target Sequences: | NM_006309 NP_006300.1 Q9Y608 |
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