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Antibodies > HSD2 / HSD11B2
HSD2 / HSD11B2 Antibody (C‑Terminus) LS‑C24601
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HSD11B2 antibody LS-C24601 is an unconjugated rabbit polyclonal antibody to rat HSD11B2 (HSD2). Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C24601-100
100 µg
$755
Performance 100% Guaranteed
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Antibody
HSD2 / HSD11B2 Antibody (C‑Terminus) LS‑C24602
Species: Rat
Applications: Western blot, ELISA

Product Description

HSD11B2 antibody LS-C24601 is an unconjugated rabbit polyclonal antibody to rat HSD11B2 (HSD2). Validated for ELISA and WB.
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Specifications

Target
Rat HSD2 / HSD11B2
Synonyms
HSD11B2, -HSD11 type II, 11-beta-HSD, 11-beta-HSD2, 11-DH2, AME1, AME, HSD2, SDR9C3, HSD11K
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 10 µg/ml)
  • ELISA (1:10000 - 1:100000)
Immunogen
HSD2 / HSD11B2 antibody was raised against a 19-aa synthetic peptide mapping near the C-terminus of rat 11b-HSD2 (1), coupled to KLH.
Epitope
C-Terminus
Specificity
Recognizes Hydroxysteroid Dehydrogenase, 11-beta Type II. No significant sequence homology is seen with 11b-HSD1 or other proteins. Species cross-reactivity: The rat peptide is not well conserved in mouse and human 11b-HSD2. We recommend the use for mouse and human 11b-HSD2, LS-C24605 and LS-C24599 respectively. See LS-C24604 for anti-HSD Type I.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml (ECL). ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well.
Presentation
100 mM Tris, pH 7.5, 0.05% Sodium Azide, 40% Glycerol, 0.2% BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
About HSD2 / HSD11B2
There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. P80365 NM_000196 NP_000187.3

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Requested From: United States
Date Requested: 11/14/2018
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