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HOXC8 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders.
Gene Name: | homeobox C8 |
Synonyms: | HOXC8, Homeo box C8, Homeobox protein Hox-C8, Hox-3.1, mouse, homolog of, HOX3A, Homeo box 3A, Homeobox C8, Homeobox protein Hox-3A, HOX3 |
Target Sequences: | NM_022658 NP_073149.1 P31273 |
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