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Catalog Number	Size	Price
LS-C744231-5	5 ml	$363

Monoclonal Mouse HMB45 Antibody (clone HMB45, IHC) LS‑C744231

Name: Anti-HMB45 Antibody | Mouse Monoclonal IHC | LSBio
Brand: Lifespan BioSciences
SKU: LS-C744231-5
Price: 363.0000 USD
Availability: InStock

Submit Review LSBio Guarantee

Antibody:

HMB45 Mouse Monoclonal (HMB45) Antibody

Application:

IHC-P

Reactivity:

Human

Format:

Unconjugated, Unmodified

$363

LS-C744231-5

Toll Free North America

206-374-1102

For Research Use Only

Specifications Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

HMB45 Mouse Monoclonal (HMB45) Antibody

Application:

IHC-P

Reactivity:

Human

Format:

Unconjugated, Unmodified

Specifications

Description

HMB45 antibody LS-C744231 is an unconjugated mouse monoclonal antibody to human HMB45. Validated for IHC.

Target

HMB45

Synonyms

HMB45 | PMEL17 | HMB-45 | HMB 45 | Human Melanoma Black | melanosomal glycoprotein gp100

See All HMB45 Antibodies

Host

Mouse

Reactivity

Human (tested or 100% immunogen sequence identity)

Clonality

IgG1 Monoclonal

Clone

HMB45

Conjugations

Unconjugated

Modifications

Unmodified

Immunogen

Extract from lymph node metastases of melanoma

Applications

IHC - Paraffin

Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.

Usage

Pre-treatment with pronase 0.1% or antigen retrieval The antibody HMB45 is used for the discrimination of Melanoma from normal Melanocytes. Melanoic Schwannoma Clear Cell Sarcoma will also be stained. Negative are tumours of epithelial, lymphoid, glial and mesenchymal origin. Melanocytes are pigmented, melanin containing cells being located mainly in the epidermis. They protect tissues from UVB irradiation of the sun. The antibody HMB45 reacts with fetal and neonatal Melanocytes, with junctional and blue naevus cells, but not with intradermal naevi and adult melanocytes. Neuraminidase-sensitive glycoconjugate on the surface of human melanosomes.

Presentation

PBS, pH 7.3, 0.09% Sodium Azide

Storage

Store at 2°C to 8°C.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

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