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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HLA‑DP/DR Antibody (clone HL‑38) IHC‑plus™ LS‑B15126
Note: This antibody replaces LS-C45848
DR antibody LS-B15126 is an unconjugated mouse monoclonal antibody to DR (HLA-DP) from human and porcine. Validated for Flow, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B15126-50
50 µg (1 mg/ml)
$425
Description
DR antibody LS-B15126 is an unconjugated mouse monoclonal antibody to DR (HLA-DP) from human and porcine. Validated for Flow, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Target
Human HLA-DP/DR
Host
Mouse
Reactivity
Human, Porcine (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal [HL-38]
Conjugations
Unconjugated. Also available conjugated with FITC, PE.
Purification
Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE.
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
HLA-DP/DR antibody was raised against raji Burkitt's lymphoma cell line.
Specificity
The antibody HL-38 recognizes common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
Usage
Western Blotting: Application note - Non-reducing conditions.
Presentation
PBS, pH 7.4, 15 mM Sodium Azide
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only.

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Images

Immunohistochemistry - Paraffin

Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry - Paraffin

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Flow Cytometry

Surface staining of human peripheral blood with anti-HLA-DR+DP (HL-38) purified, GAM-APC.
Surface staining of human peripheral blood with anti-HLA-DR+DP (HL-38) purified, GAM-APC.

Immunohistochemistry - Paraffin

Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry - Paraffin

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Flow Cytometry

Surface staining of human peripheral blood with anti-HLA-DR+DP (HL-38) purified, GAM-APC.
Surface staining of human peripheral blood with anti-HLA-DR+DP (HL-38) purified, GAM-APC.

Immunohistochemistry - Paraffin

Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry - Paraffin

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Flow Cytometry

Surface staining of human peripheral blood with anti-HLA-DR+DP (HL-38) purified, GAM-APC.
Surface staining of human peripheral blood with anti-HLA-DR+DP (HL-38) purified, GAM-APC.

Immunohistochemistry - Paraffin

Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine, MALT: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemistry - Paraffin

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Flow Cytometry

Surface staining of human peripheral blood with anti-HLA-DR+DP (HL-38) purified, GAM-APC.
Surface staining of human peripheral blood with anti-HLA-DR+DP (HL-38) purified, GAM-APC.

Requested From: United States
Date Requested: 12/19/2018
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