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HLA-DOB

major histocompatibility complex, class II, DO beta

HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

Gene Name: major histocompatibility complex, class II, DO beta
Synonyms: HLA-DOB, DOB, MHC class II antigen DOB
Target Sequences: NM_002120 NP_002111.1 P13765

☰ Filters
Antibodies (25)
Proteins (5)
Over-Expression Lysate (2)
Primary (25)
Recombinant (3)
HLA-DOB (30)
Human (25)
Mouse (4)
Rat (4)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Horse (3)
Monkey (3)
Orangutan (3)
Pig (3)
Rabbit (3)
Sheep (3)
IHC (2)
WB (24)
ELISA (6)
IF (1)
IP (1)
Peptide-ELISA (3)
rabbit (21)
mouse (4)
IgG (16)
IgG1 (3)
monoclonal mc (3)
polyclonal pc (22)
DOB 10E6/5 (3)
APC Conjugated (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (15)
N-Terminus (5)
10-90 aa, N-terminal (1)
aa1-50 (1)
aa33-82 (1)
aa43-88 (1)
No (30)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
HLA-DOB Antibody - Western blot analysis of extracts of various cell lines, using HLA-DOB antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
HLA-DOB Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
HLA-DOB Protein - Purified recombinant protein HLA-DOB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
30.6 kDa
20 µg/$1,107
HLA-DOB Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using HLA-DOB Polyclonal Antibody at dilution of 1:40(×200)
Select
HLA-DOB Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HLA-DOB Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
Select
HLA-DOB Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HLA-DOB Antibody - Immunohistochemistry of paraffin-embedded Human tonsil tissue  using HLA-DOB Polyclonal Antibody at dilution of 1:45(×200)
Select
HLA-DOB Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
HLA-DOB Mouse anti-Human Monoclonal (DOB 10E6/5) Antibody
Human
ELISA, WB
Unconjugated
200 µg/$480
HLA-DOB Antibody - Western blot of HLA-DO beta antibody
Select
HLA-DOB Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
HLA-DOB Mouse anti-Human Monoclonal (FITC) (DOB 10E6/5) Antibody
Human
ELISA, WB
FITC Conjugated
100 µg/$409
Select
HLA-DOB Mouse anti-Human Monoclonal (Biotin) (DOB 10E6/5) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µg/$396
Select
HLA-DOB Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
Select
HLA-DOB Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
HLA-DOB Antibody - Western blot analysis of the lysates from HeLa cells using HLA-DOB antibody.
Select
HLA-DOB Rabbit anti-Human Polyclonal (aa33-82) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
HLA-DOB Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
HLA-DOB Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
HLA-DOB Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
HLA-DOB Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
HLA-DOB Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
Select
HLA-DOB Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
Select
HLA-DOB Rabbit anti-Human Polyclonal (aa43-88) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
HLA-DOB Antibody - HLA-DOB antibody Western Blot of HepG2. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HLA-DOB Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
HLA-DOB Antibody - HLA-DOB antibody Western Blot of HepG2. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HLA-DOB Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Dog, Sheep, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
HLA-DOB Antibody - HLA-DOB antibody Western Blot of HepG2. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
HLA-DOB Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Dog, Sheep, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
HLA-DOB Antibody - Western blot analysis of HLA-DOB expression in HeLa (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
Select
HLA-DOB Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
HLA-DOB Antibody - Western blot analysis of extracts of various cell lines, using HLA-DOB antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
HLA-DOB Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
HLA-DOB Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 30 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).