Human GYPA / CD235a / Glycophorin A

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Recombinant Monoclonal

rGYPA/280

Unconjugated

Protein A/G purified

Azide-free, Carrier-free. Also available Unmodified.

Recombinant full-length human glycophorin A protein. Antigen Molecular Weight: 39 kDa

Recognizes a sialoglycoprotein of 39 kDa , identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

• IHC - Paraffin (0.25 - 0.5 µg/ml)

Immunohistology (Formalin-fixed - 0.25-0.5 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.

10 mM PBS

Store at -20°C to -80°C for up to 2 years.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P02724 NCBI: NM_002099 NP_002090.4