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Catalog Number Size Price
LS-C43151-0.1 0.1 ml $525 
Antibody

Polyclonal Rabbit anti‑Rat GRIA2 / GLUR2 Antibody (WB) LS‑C43151

Polyclonal Rabbit anti‑Rat GRIA2 / GLUR2 Antibody (WB) LS‑C43151

Antibody:
GRIA2 / GLUR2 Rabbit anti-Rat Polyclonal Antibody
Application:
WB
Reactivity:
Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$525
LS-C43151-0.1
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
GRIA2 / GLUR2 Rabbit anti-Rat Polyclonal Antibody
Application:
WB
Reactivity:
Rat
Format:
Unconjugated, Unmodified

Specifications

Description
GLUR2 antibody LS-C43151 is an unconjugated rabbit polyclonal antibody to rat GLUR2 (GRIA2). Validated for WB.
Target
Rat GRIA2 / GLUR2
Synonyms
GRIA2 | AMPA 2 | GluR-K2 | Glutamate receptor 2 | HBGR2 | GluA2 | GluR-2 | GluR-B | GLUR2 | GLURB
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Immunogen
Keyhole limpet hemocyanin conjugated synthetic peptide corresponding to an amino acid sequence within rat GluR2.
Specificity
Recognizes glutamate receptor subunit 2 (GluR2), a component of the AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid) group of ionotropic glutamate receptors, which play a key role at excitatory synapses, including synaptic transmission, stabilization and plasticity. GluR2 is possibly the most important of the AMPA receptor subunits, responsible for AMPA receptor rectifying properties, control of ion flow and in particular the influx of calcium. The majority of GluR2 in the CNS is expressed in the GluR2(R) form, containing a critical arginine residue (as opposed to a glutamine residue) in the Transmembrane region 2 (TM2) domain, thereby rendering native AMPA receptors impermeable to calcium.
Applications
  • Western blot (1:1000)
Usage
Western Blot: LS-C43151 detects a band of approximately 100 kD in rat brain hippocampus cell lysates.
Presentation
10mM HEPES, pH 7.5, 0.09% Sodium Azide, 50% Glycerol, 0.01% BSA
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GRIA2 / GLUR2
P42262 NM_000826 NP_000817.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 9/17/2021