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Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling.
Gene Name: | NCK adaptor protein 2 |
Synonyms: | NCK2, GRB4, NCKbeta, NCK beta, Nck-2, Cytoplasmic protein NCK2, NCK adaptor protein 2 |
Target Sequences: | NM_003581 NP_003572.2 O43639 |
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