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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
Gene Name: | glypican 4 |
Synonyms: | GPC4, DJ900E8.1 (glypican 4), Glypican 4, Glypican proteoglycan 4, Glypican-4, K-glypican |
Target Sequences: | NM_001448 NP_001439.2 O75487 |
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