Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IHC (1:1000 - 1:5000)
Western blot (1:2000 - 1:10000)
Specificity and Use
IgM Fc5mu antibody was raised against human IgM Fc5mu fragment.
anti-Peroxidase, anti-Goat Serum, Human IgM and Human Serum. No reaction was observed against anti- Pepsin, anti-Goat IgG F(c), Human IgG or Human IgA. Specificity was confirmed by ELISA at less than 1 % cross reactivity against other human heavy or light chain isotypes
Suitable for immunoblotting (western or dot blot), ELISA, immunoperoxidase electron microscopy and immunohistochemistry as well as other peroxidase-antibody based enzymatic assays requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.
0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 10 mg/ml BSA (IgG, protease free), 0.01% Thimerosal.