Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IHC (1:500 - 1:2500)
Western blot (1:1000 - 1:10000)
ELISA (1:2000 - 1:8000)
Specificity and Use
Human IgG, IgA, and IgM whole molecules.
Recognizes Human IgG, IgA and IgM (HalphaL), (all Human immunoglobulin classes, isotypes and chain combinations). Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-peroxidase and anti-goat serum. No reaction was detected against anti-goat IgG F(c), or mouse serum proteins.
Suitable for use in Western Blot, Dot Blot, ELISA, Immunoperoxidase electron microscopy and Immunohistochemistry. ELISA: 1:2000-1:8000 using ABTS as a substrate for 30 min at RT. Western Blot:1:1000-1:10000. Immunohistochemistry: 1:500-1:2500.