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Gastric Inhibitory Peptide is an incretin hormone and belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion.
Gene Name: | gastric inhibitory polypeptide |
Synonyms: | GIP, Incretin hormone, Gastric inhibitory polypeptide |
Target Sequences: | NM_004123 NP_004114.1 P09681 |
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