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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FOLR1 / Folate Receptor Alpha Antibody (Internal) LS‑C352204
Folate Receptor Alpha antibody LS-C352204 is an unconjugated rabbit polyclonal antibody to Folate Receptor Alpha (FOLR1) from human and monkey. Validated for IP and WB.
Catalog
Size
Price
LS-C352204-100
100 µl (1 mg/ml)
$245

Popular FOLR1 / Folate Receptor Alpha Products

Antibody
Species: Human
Applications: ICC, Western blot, Flow Cytometry, ELISA
Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Human
Applications: IHC, Western blot, Flow Cytometry, ELISA
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human
Applications: IHC - Paraffin, Western blot

Product Description

Folate Receptor Alpha antibody LS-C352204 is an unconjugated rabbit polyclonal antibody to Folate Receptor Alpha (FOLR1) from human and monkey. Validated for IP and WB.

Specifications

Target
Human FOLR1 / Folate Receptor Alpha
Synonyms
FOLR1, Adult folate-binding protein, FBP, Folate receptor alpha, KB cells FBP, Folate binding protein, Folate receptor 1, Folate receptor 1 (adult), Folate receptor, adult, FOLR, FR-alpha
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation (1:10 - 1:100)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human FR alpha.
Blocking Peptide
LS-E41350 - Lyophilized - 1 mg - $145.00
Immunizing peptide used to generate LS-C352204. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Internal
Specificity
Recognizes endogenous levels of FR alpha protein.
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only.
About FOLR1 / Folate Receptor Alpha
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. P15328 NM_016730 NP_057942.1


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Images

Western blot

Western blot analysis of FR alpha expression in A431 (A); HeLa (B); HepG2 (C); JAR (D) whole cell lysates.
Western blot analysis of FR alpha expression in A431 (A); HeLa (B); HepG2 (C); JAR (D) whole cell lysates.

Western blot

Western blot analysis of FR alpha expression in A431 (A); HeLa (B); HepG2 (C); JAR (D) whole cell lysates.
Western blot analysis of FR alpha expression in A431 (A); HeLa (B); HepG2 (C); JAR (D) whole cell lysates.

Western blot

Western blot analysis of FR alpha expression in A431 (A); HeLa (B); HepG2 (C); JAR (D) whole cell lysates.
Western blot analysis of FR alpha expression in A431 (A); HeLa (B); HepG2 (C); JAR (D) whole cell lysates.

Western blot

Western blot analysis of FR alpha expression in A431 (A); HeLa (B); HepG2 (C); JAR (D) whole cell lysates.
Western blot analysis of FR alpha expression in A431 (A); HeLa (B); HepG2 (C); JAR (D) whole cell lysates.

Requested From: United States
Date Requested: 11/15/2018

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