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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FcERI / Fc Epsilon RI Antibody (aa35‑84, HRP) LS‑C447444
Fc Epsilon RI antibody LS-C447444 is an HRP-conjugated rabbit polyclonal antibody to Fc Epsilon RI (FcERI) from human, chimpanzee and gibbon. Validated for WB.
Catalog
Size
Price
LS-C447444-100
100 µl (0.65 mg/ml)
$385

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Product Description

Fc Epsilon RI antibody LS-C447444 is an HRP-conjugated rabbit polyclonal antibody to Fc Epsilon RI (FcERI) from human, chimpanzee and gibbon. Validated for WB.

Specifications

Target
Human FcERI / Fc Epsilon RI
Synonyms
FCER1A, Alpha polypeptide, FCE1A, FcERI, Fc Epsilon RI, Fc epsilon RI alpha-chain, Fc-epsilon RI-alpha, IgE Fc receptor subunit alpha
Host
Rabbit
Reactivity
Human, Chimpanzee, Gibbon (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Horseradish Peroxidase. Also available Unconjugated or conjugated with Biotin, FITC.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide located between aa35-84 of human FCER1A (P12319, NP_001992). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon (100%); Gorilla, Monkey (85%).
Epitope
aa35-84
Specificity
Human FCER1A
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
100 mM sodium phosphate, pH 7.6, 150 mM NaCl
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
About FcERI / Fc Epsilon RI
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. P12319 NM_002001 NP_001992.1


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Images

Western blot

FCER1A antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
FCER1A antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

FCER1A antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
FCER1A antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

FCER1A antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
FCER1A antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

FCER1A antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
FCER1A antibody Western blot of 721_B cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 11/13/2018

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