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Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
Gene Name: | F-box and WD repeat domain containing 10 |
Family/Subfamily: | F-Box |
Synonyms: | FBXW10, Fbw10, HREP, SM25H2, C17ORF1, C17ORF1A, SM2SH2 |
Target Sequences: | NM_031456 NP_113644.3 Q5XX13 |
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