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FAR2 belongs to the short chain dehydrogenase/reductase superfamily. It encodes a reductase enzyme involved in the first step of wax biosynthesis wherein fatty acids are converted to fatty alcohols. The encoded peroxisomal protein utilizes saturated fatty acids of 16 or 18 carbons as preferred substrates. Alternatively spliced transcript variants have been observed for this gene. Related pseudogenes have been identified on chromosomes 2, 14 and 22.
Gene Name: | fatty acyl CoA reductase 2 |
Synonyms: | FAR2, Fatty acyl-CoA reductase 2, MLSTD1, Fatty acyl CoA reductase 2, SDR10E2 |
Target Sequences: | NM_018099 NP_060569.3 Q96K12 |
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