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F8A1 / HAP40 is contained entirely within intron 22 of the factor VIII gene; spans less than 2 kb, and is transcribed in the direction opposite of factor VIII. A portion of intron 22 (int22h), containing F8A, is repeated twice extragenically closer to the Xq telomere. Although its function is unknown, the observation that this gene is conserved in the mouse implies it has some function. Unlike factor VIII, this gene is transcribed abundantly in a wide variety of cell types.
Gene Name: | coagulation factor VIII-associated 1 |
Synonyms: | F8A1, CpG island protein, DXS522E, Factor VIII associated protein, F8A, Factor VIII intron 22 protein, HAP40 |
Target Sequences: | NM_012151 NP_036283.2 P23610 |
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