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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ERGIC‑53 / LMAN1 Antibody (aa36‑85, Biotin) LS‑C449041
LMAN1 antibody LS-C449041 is a biotin-conjugated rabbit polyclonal antibody to LMAN1 (ERGIC-53) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C449041-100
100 µl (1 mg/ml)
$385

Popular ERGIC-53 / LMAN1 Products

Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Chicken
Applications: Western blot
IHC of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Species: Human, Monkey, Rat, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Monkey
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:50.
Species: Human, Monkey, Rat, Dog
Applications: IHC, IHC - Paraffin, Western blot
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Species: Human, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry

Product Description

LMAN1 antibody LS-C449041 is a biotin-conjugated rabbit polyclonal antibody to LMAN1 (ERGIC-53) from human, mouse, rat and other species. Validated for WB.

Specifications

Target
Human ERGIC-53 / LMAN1
Synonyms
LMAN1, ERGIC53, F5F8D, gp58, ERGIC-53, FMFD1, Lectin mannose-binding 1, MCFD1, MR60, Protein ERGIC-53, Lectin, mannose-binding, 1
Host
Rabbit
Reactivity
Human, Gibbon, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Chicken (tested or 100% immunogen sequence identity)
Predicted
Guinea pig, Rabbit, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide located between aa36-85 of human LMAN1 (P49257, NP_005561). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Horse, Pig, Opossum, Zebra finch, Chicken (100%); Rabbit, Guinea pig, Xenopus, Stickleback, Zebrafish (92%).
Epitope
aa36-85
Specificity
Human LMAN1
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
About ERGIC-53 / LMAN1
ERGIC-53 / LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. P49257 NM_005570 NP_005561.1


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Images

Western blot

Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 11/15/2018

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