Recombinant Monoclonal Rabbit anti‑Human EPCAM Antibody (clone EGP40/1555R, Azide‑free,Carrier‑free, N‑Terminus, aa 20‑60, IHC) LS‑C751258
Recombinant Monoclonal Rabbit anti‑Human EPCAM Antibody (clone EGP40/1555R, Azide‑free,Carrier‑free, N‑Terminus, aa 20‑60, IHC) LS‑C751258
Antibody:
EPCAM Rabbit anti-Human Recombinant Monoclonal (N-Terminus, aa 20-60) (Azide-free, Carrier-free) (EGP40/1555R) Antibody
Format:
Unconjugated, Azide-free, Carrier-free
Overview
Antibody:
EPCAM Rabbit anti-Human Recombinant Monoclonal (N-Terminus, aa 20-60) (Azide-free, Carrier-free) (EGP40/1555R) Antibody
Format:
Unconjugated, Azide-free, Carrier-free
Specifications
Description
EPCAM antibody LS-C751258 is an unconjugated rabbit recombinant monoclonal antibody to human EPCAM (N-Terminus, aa 20-60). Validated for Flow and IHC.
Target
Human EPCAM
Synonyms
EPCAM | 323/A3 | ACSTD1 | 17-1A | CD326 | EGP | EGP34 | Epithelial glycoprotein | GA733-2 | HNPCC8 | Ep-CAM | ESA | HEGP314 | KS 1/4 antigen | KS1/4 | KSA | M1S2 | MIC18 | MK-1 | MH99 | TROP1 | TACST-1 | TACSTD1 | CD326 antigen | CO-17A | DIAR5 | EGP-2 | EGP314 | EGP40 | Epithelial glycoprotein 314 | HEA125 | Ly74 | M4S1
Reactivity
Human
(tested or 100% immunogen sequence identity)
Non-Reactivity
Mouse, Rat
Clonality
IgG
Recombinant Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Azide-free, Carrier-free.
Also available
Unmodified.
Immunogen
A synthetic peptide (around aa 20-60) from the N-Terminus of human TACSTD1 protein. Antigen Molecular Weight: 40-43 kDa
Epitope
N-Terminus, aa 20-60
Specificity
Recognizes a 40-43 kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (EpCAM). EpCAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
Applications
- IHC - Paraffin (1 - 2 µg/ml)
- Flow Cytometry (1 - 2 µg/10E6 cells)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Usage
Immunohistology (Formalin-fixed - 1-2 ug/ml for 30 min at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Storage
Store at -20°C to -80°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Mouse
Applications:
IHC, IHC - Frozen, ICC, Western blot, Immunoprecipitation, Flow Cytometry
Species:
Human
Applications:
IHC - Frozen, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Species:
Pig
Applications:
Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/6/2024