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EIF4EBP3 is a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.
Gene Name: | eukaryotic translation initiation factor 4E binding protein 3 |
Synonyms: | EIF4EBP3, 4EBP3, 4E-BP3, EIF4E-binding protein 3 |
Target Sequences: | NM_003732 NP_003723.1 O60516 |
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