EIF2S1 antibody LS-C498760 is a biotin-conjugated rabbit polyclonal antibody to human EIF2S1. Validated for ELISA.
(tested or 100% immunogen sequence identity)
Also available Unconjugated
or conjugated with HRP
Protein G purified
- (applications tested for the base form of this product only)
EIF2S1 antibody was raised against recombinant Human Eukaryotic translation initiation factor 2 subunit 1 protein (276-315AA)
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
For research use only.