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| Catalog Number | Size | Price |
|---|---|---|
| LS-C357824-25 | 25 µg (0.5 mg/ml) | $364 |
| LS-C357824-100 | 100 µg (0.5 mg/ml) | $511 |
Polyclonal Rabbit anti‑Human CYLD Antibody (N‑Terminus, WB) LS‑C357824
Polyclonal Rabbit anti‑Human CYLD Antibody (N‑Terminus, WB) LS‑C357824
Antibody:
CYLD Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
CYLD Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Specifications
Description
CYLD antibody LS-C357824 is an unconjugated rabbit polyclonal antibody to CYLD (N-Terminus) from human. It is reactive with human and mouse. Validated for WB.
Target
Human CYLD
Synonyms
CYLD | CDMT | Deubiquitinating enzyme CYLD | CYLDI | EAC | HSPC057 | MFT1 | MFT | SBS | TEM | BRSS | Ubiquitin thiolesterase CYLD | USPL2 | CYLD1 | KIAA0849 | Ubiquitin thioesterase CYLD
Host
Rabbit
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
A recombinant protein fragment from the N-Terminus of human CYLD.
Epitope
N-Terminus
Specificity
Human CYLD
Applications
- Western blot (2 - 5 µg/ml)
Usage
CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
Presentation
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CYLD
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Mouse, Rat, Hamster
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC - Paraffin, Western blot, Flow Cytometry
Species:
Human, Monkey, Mouse, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit, Chicken
Applications:
ICC, Western blot
![CYLD Antibody - Immunofluorescence of monoclonal antibody to CYLD on HeLa cell . [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com//image2/cyld-antibody-clone-2c3-ls-c197008/144478_562719.jpg)
Species:
Human, Rat, Bovine, Horse, Pig, Sheep
Applications:
Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/26/2024
Date Requested: 4/26/2024
