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Catalog Number Size Price
LS-C357824-25 25 µg (0.5 mg/ml) $323 
LS-C357824-100 100 µg (0.5 mg/ml) $452 
CYLD Antibody - CYLD antibody western blot with human samples

Polyclonal Rabbit anti‑Human CYLD Antibody (N‑Terminus, WB) LS‑C357824

Polyclonal Rabbit anti‑Human CYLD Antibody (N‑Terminus, WB) LS‑C357824

Antibody:
CYLD Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified
Price
Catalog Number
$323
LS-C357824-25
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
CYLD Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Application:
WB
Reactivity:
Human, Mouse
Format:
Unconjugated, Unmodified

Specifications

Description
CYLD antibody LS-C357824 is an unconjugated rabbit polyclonal antibody to CYLD (N-Terminus) from human. It is reactive with human and mouse. Validated for WB.
Target
Human CYLD
Synonyms
CYLD | CDMT | Deubiquitinating enzyme CYLD | CYLDI | EAC | HSPC057 | MFT1 | MFT | SBS | TEM | BRSS | Ubiquitin thiolesterase CYLD | USPL2 | CYLD1 | KIAA0849 | Ubiquitin thioesterase CYLD
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Immunogen
A recombinant protein fragment from the N-Terminus of human CYLD.
Epitope
N-Terminus
Specificity
Human CYLD
Applications
  • Western blot (2 - 5 µg/ml)
Usage
CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
Presentation
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CYLD
Q9NQC7 NM_015247 CAB93533.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 11/28/2021