CYLD | CDMT | Deubiquitinating enzyme CYLD | CYLDI | EAC | HSPC057 | MFT1 | MFT | SBS | TEM | BRSS | Ubiquitin thiolesterase CYLD | USPL2 | CYLD1 | KIAA0849 | Ubiquitin thioesterase CYLD
(tested or 100% immunogen sequence identity)
Protein A purified
A recombinant protein fragment from the N-Terminus of human CYLD.
- Western blot (2 - 5 µg/ml)
CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
1X PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% Sodium Azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only. Intended for use by laboratory professionals.
This antibody carries the LSBio 100% Guarantee.