CXCR2 | CDw128b | CD182 antigen | CMKAR2 | CXCR-2 | CD182 | CXC-R2 | IL-8R B | Il-8 receptor b | IL-8 receptor type 2 | Il-8rb | IL8R2 | IL8RB | Interleukin-8 receptor type B | GRO/MGSA receptor | Interleukin 8 receptor beta | Interleukin 8 receptor, beta | Chemokine (CXC) receptor 2 | IL8RA | Interleukin 8 receptor B | Interleukin 8 receptor type 2
Human, Mouse, Rat
(tested or 100% immunogen sequence identity)
- Western blot (0.5 - 1 µg/ml)
Synthetic peptide (CYEDMGNNTANWRMLLR, aa196-212 of UniProt P25025) was used as the immunogen for this CXCR2 antibody. Percent identity by BLAST analysis: Human (100%); Elephant, Rabbit (82%); Mouse, Rat (65%).
CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitute in sterile distilled water.
After reconstitution, may be stored at 4°C for 1 month. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C.
For research use only. Intended for use by laboratory professionals.
This antibody carries the LSBio 100% Guarantee.