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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CSA / ERCC8 Antibody (aa210‑238) LS‑C321168
ERCC8 antibody LS-C321168 is an unconjugated rabbit polyclonal antibody to ERCC8 (CSA) from human and mouse. Validated for ELISA, IHC and WB.
Antibody
Catalog
Size
Price
LS-C321168-200
200 µl
$530

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Product Description

CSA / ERCC8 Antibody (aa210-238) for IHC, WB/Western, ELISA LS-C321168

Specifications

Target
Human CSA / ERCC8
Synonyms
ERCC8, CKN1, UVSS2, CSA
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Affinity purified
Modifications
Unmodified. Also available Azide-free.
Applications
  • IHC (1:50 - 1:100)
  • Western blot (1:100 - 1:500)
  • ELISA (1:1000)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Epitope
aa210-238
Specificity
This ERCC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of human ERCC8.
Presentation
PBS, pH 7.2, 0.09% Sodium Azide
Storage
May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for 1 year.
Restrictions
For research use only.
About CSA / ERCC8
Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. Q13216 NM_000082 NP_000073.1


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Requested From: United States
Date Requested: 10/17/2018

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