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May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected cells, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes.
Gene Name: | coronin, actin binding protein, 1A |
Synonyms: | CORO1A, Clipin-A, Coronin-like protein A, Coronin-like protein p57, CLIPINA, Coronin-1, Coronin-1A, HCORO1, p57, TACO, CLABP, CORO1 |
Target Sequences: | NM_007074 NP_009005.1 P31146 |
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