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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CLDN2 / Claudin 2 Antibody (C-Terminus) IHC-plus™ LS-B7756

Best Seller
Note: This antibody replaces LS-C6145
Claudin 2 antibody LS-B7756 is an unconjugated mouse monoclonal antibody to Claudin 2 (CLDN2) from human, mouse, rat and other species. Validated for IF, IHC and WB.
Catalog
Size
Price
LS-B7756-50
50 µg (0.5 mg/ml)
$485
Description
Claudin 2 antibody LS-B7756 is an unconjugated mouse monoclonal antibody to Claudin 2 (CLDN2) from human, mouse, rat and other species. Validated for IF, IHC and WB.
Target
Mouse CLDN2 / Claudin 2
Host
Mouse
Reactivity
Mouse, Human, Rat, Dog (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 µg/ml)
  • Immunofluorescence
  • Western blot
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
A synthetic peptide corresponding to a 26 amino acid sequence at the C-terminus of the mouse Claudin-2 protein.
Epitope
C-Terminus
Specificity
Reacts with the ~22-23kD Claudin-2 protein. This antibody is confirmed reactive with human, mouse, rat and canine. Reactivity is confirmed from extracts of liver and kidney tissues in all four species as well as MDCK and Caco-2 cell lysates. Reactivity with other species has not been determined.
Usage
Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Immunofluorescence (Rat): 1-3 ug/ml. Western Blot (Human, mouse, rat, canine): 1-3 ug/ml. Immunohistochemistry (Formalin-fixed paraffin embedded tissues): 1-2 ug/ml; Confirmed with human normal colon, spleen and thyroid, colon and breast cancer tissues. Heat induced epitope retrieval with EDTA buffer, pH 8, is required prior to staining.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CLDN2 / Claudin 2
P57739 NM_020384 NP_065117.1

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Immunohistochemistry

Anti-CLDN2 / Claudin 2 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Anti-CLDN2 / Claudin 2 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.

Immunohistochemistry

Anti-CLDN2 / Claudin 2 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Anti-CLDN2 / Claudin 2 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.

Immunohistochemistry

Anti-CLDN2 / Claudin 2 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Anti-CLDN2 / Claudin 2 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.

Immunohistochemistry

Anti-CLDN2 / Claudin 2 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Anti-CLDN2 / Claudin 2 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.

Requested From: United States
Date Requested: 4/25/2019
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