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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ClC‑3 / CLCN3 Antibody (C‑Terminus) LS‑C6124
Antibody
CLCN3 antibody LS-C6124 is an unconjugated rabbit polyclonal antibody to CLCN3 (ClC-3) from human, mouse, rat and other species. Validated for ELISA and WB.
Catalog
Size
Price
LS-C6124-50
50 µl
Unavailable

Popular ClC-3 / CLCN3 Products

CLCN3 antibody LS-C31442 was used in IHC to stain formalin-fixed, paraffin-embedded human brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse, Rat
Applications: IHC, ICC, Western blot
Antibody
Species: Rat, Human, Mouse
Applications: IHC, ICC, Western blot
Antibody
Species: Rat, Human, Mouse
Applications: IHC, ICC, Western blot
Antibody
Species: Rat, Human, Mouse
Applications: IHC, ICC, Western blot

Product Description

CLCN3 antibody LS-C6124 is an unconjugated rabbit polyclonal antibody to CLCN3 (ClC-3) from human, mouse, rat and other species. Validated for ELISA and WB.
About ClC-3 / CLCN3
ClC-3 / CLCN3 is a member of the voltage-gated chloride channel (ClC) family. The encoded protein is present in all cell types and localized in plasma membranes and in intracellular vesicles. It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains. The ClC domain catalyzes the selective flow of Cl- ions across cell membranes, and the CBS domain may have a regulatory function. P51790 NM_001829 NP_001820.2

CLCN3 Antibody, Chloride channel protein 3 Antibody, ClC-3 Antibody, Chloride channel 3 Antibody, Chloride transporter ClC-3 Antibody, CLC3 Antibody


Specifications

Target
Rat ClC-3 / CLCN3
Host
Rabbit
Reactivity
Rat, Human, Mouse, Rabbit, Frog (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:1000 - 1:5000)
  • ELISA (1:10000 - 1:50000)
Immunogen
ClC-3 / CLCN3 antibody was raised against synthetic peptide consisting of 18aa sequence near the C-terminus of rat CLC-3 (KLH coupled). The peptide has no significant sequence homology is detected with other CLCs or other proteins. There is high degree of sequence homology between CLC3, CLC4 and CLC5.
Epitope
C-Terminus
Specificity
Recognizes rat CLC3. Species sequence Homology: Mouse, guinea pig, rat, human, rabbit and frog CLC-3:100%.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000-1:5000 (ECL). ELISA: 1:10000-1:50000. Control peptide can be used to coat ELISA plates at 1 ug/ml.
Presentation
Neat serum, 0.1% sodium azide, 40% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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