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CHMP1B

Charged Multivesicular Body Protein 1B

Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.

Gene Name: Charged Multivesicular Body Protein 1B
Synonyms: CHMP1B, C18orf2, C18-ORF2, CHMP1.5, Chromatin-modifying protein 1b, Vacuolar protein sorting 46-2, Vps46-2, Vps46B, Chromatin modifying protein 1B, HVps46-2
Target Sequences: NM_020412 AAG01449.1 Q7LBR1

☰ Filters
Antibodies (9)
Proteins (6)
Over-Expression Lysate (2)
Primary (9)
Recombinant (4)
CHMP1B (15)
Human (9)
Mouse (6)
Rat (6)
Bat (3)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Drosophila (3)
Horse (3)
Xenopus (3)
Zebrafish (3)
IHC (4)
IHC-P (2)
WB (8)
ELISA (2)
IF (1)
Peptide-ELISA (1)
rabbit (9)
IgG (4)
polyclonal pc (9)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (6)
aa35-84 (4)
aa1-199 (1)
No (15)
GST (1)
GST, N-terminus (2)
His (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (3)
CHMP1B Protein
Select
E. coli
His
20 µg/$361; 100 µg/$739; 10 µg/$292; 50 µg/$523; 250 µg/$1,285; 500 µg/$1,917
Select
CHMP1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
CHMP1B Antibody - Immunohistochemistry of paraffin-embedded mouse kidney tissue.
Select
CHMP1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CHMP1B Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
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CHMP1B Rabbit anti-Human Polyclonal (aa1-199) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CHMP1B Antibody - Western blot analysis of extracts of B16F10 cells using CHMP1B antibody. The lane on the left was treated with blocking peptide.
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CHMP1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CHMP1B Antibody - Immunohistochemical analysis of CHMP1B staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CHMP1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
CHMP1B Antibody - CHMP1B antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHMP1B Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
CHMP1B Antibody - CHMP1B antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHMP1B Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Drosophila, Bat, Bovine, Mouse, Rat, Horse, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
CHMP1B Antibody - CHMP1B antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CHMP1B Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Drosophila, Bat, Bovine, Mouse, Rat, Horse, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
CHMP1B Antibody - CHMP1B antibody Western blot of Fetal Heart lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CHMP1B Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Drosophila, Bat, Bovine, Mouse, Rat, Horse, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
CHMP1B Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CHMP1B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.9 kDa
20 µg/$150
CHMP1B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
21.9 kDa
100 µg/$494
CHMP1B Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CHMP1B Protein - 12.5% SDS-PAGE of human CHMP1B stained with Coomassie Blue
Select
Wheat Germ Extract
GST
48.5 kDa
10 µg/$479; 25 µg/$670
Viewing 1-15 of 15 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).