Human CGB / hCG Beta
CGB | CGB3 | CG-beta | HCGB | hCG Beta
(tested or 100% immunogen sequence identity)
Ion exchange chromatography
Chorionic Gonadotropin Beta subunit.
Recognizes the beta subunit of human chorionic gonadotropin (hCG). Minimal cross-reactivity (0.5%) has been observed with the intact hCG molecule and negligible reactivity has been shown with the human luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH). Human chorionic gonadotropin exists in 5 different variants (hCG, sulfated hCG, hyperglycosylated hCG, free beta hCG and hyperglycosylated free beta) that share the same amino acid sequence but have different functions. hCG is a glycoprotein of 237 amino acids. Regular hCG has a molecular weight of ~36kD where oligosaccharides account for 25-30% of the MW. hCG is composed of a 92-amino acid alpha subunit, common to the LH, FSH and TSH hormones, and of a unique beta subunit, which is recognized byProduction of progesterone is not the only role of hCG: it also has numerous other functions, during pregnancy and as a marker for certain cancers, and.