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Catalog Number Size Price
LS-C44953-0.1 0.1 mg (0.1 mg/ml) $432 
Antibody

Monoclonal Mouse anti‑Human CD79A / CD79 Alpha Antibody (clone HM57, FITC, Cytoplasmic Domain) LS‑C44953

Monoclonal Mouse anti‑Human CD79A / CD79 Alpha Antibody (clone HM57, FITC, Cytoplasmic Domain) LS‑C44953

Note: This antibody replaces LS-C58125
Antibody:
CD79A / CD79 Alpha Mouse anti-Human Monoclonal (Cytoplasmic Domain) (FITC) (HM57) Antibody
Application:
Flo
Reactivity:
Human
Format:
FITC, Unmodified
Price
Catalog Number
$432
LS-C44953-0.1
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
CD79A / CD79 Alpha Mouse anti-Human Monoclonal (Cytoplasmic Domain) (FITC) (HM57) Antibody
Application:
Flo
Reactivity:
Human
Format:
FITC, Unmodified

Specifications

Description
CD79 Alpha antibody LS-C44953 is an FITC-conjugated mouse monoclonal antibody to human CD79 Alpha (CD79A) (Cytoplasmic Domain). Validated for Flow. Cited in 2 publications.
Target
Human CD79A / CD79 Alpha
Synonyms
CD79A | CD79a antigen | Ig-alpha | MB-1 | MB-1 membrane glycoprotein | Surface IgM-associated protein | MB1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
HM57
Conjugations
FITC
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1
Epitope
Cytoplasmic Domain
Specificity
Recognizes an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin
Applications
  • Flow Cytometry (1:1 - 1:5)
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Membrane permeabilization is required for this application. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% Sodium Azide, 1% BSA
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About CD79A / CD79 Alpha
P11912 NM_021601 NP_001774.1

LSBio Ratings

CD79A / CD79 Alpha Antibody (Cytoplasmic Domain, clone HM57, FITC) for Flow LS-C44953 has an LSBio Rating of
Publications (4.1)

Publications (2)

Broad feedback inhibition of pre-B-cell receptor signaling components. Hauser J, Verma-Gaur J, Grundstr[Character f6]m T. Molecular immunology. 2013 Jul;54:247-53.

Negative feedback regulation of antigen receptors through calmodulin inhibition of E2A. Verma-Gaur J, Hauser J, Grundström T. Journal of immunology (Baltimore, Md. : 1950). 2012 188:6175-83. (WB; Mouse)

Customer Reviews (0)


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Requested From: United States
Date Requested: 4/27/2024