Human CD244

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

2B4.69

Unconjugated

Protein G purified

Low Endotoxin

CD244 Fusion protein

Specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKR2B4). The glycoprotein CD244 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. CD244 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.

• Immunoprecipitation
• Flow Cytometry (1:50 - 1:200)

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1x10^6 cells in 100 ul. Method sheets are available on request.

PBS

Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q9BZW8 NCBI: NM_016382 NP_057466.1