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Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
Gene Name: | bone marrow stromal cell antigen 1 |
Synonyms: | BST1, ADP-ribosyl cyclase 2, Bone marrow stromal antigen 1, BST-1, CD157 antigen, CADPr hydrolase 2, CD157, Cyclic ADP-ribose hydrolase 2, NAD(+) nucleosidase |
Target Sequences: | NM_004334 NP_004325.2 Q10588 |
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