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Calgizzarin / S100A11 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
Gene Name: | S100 calcium binding protein A11 |
Synonyms: | S100A11, Calgizzarin, MLN 70, MLN70, Protein S100-A11, Protein S100-C, S100C |
Target Sequences: | NM_005620 NP_005611.1 P31949 |
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