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Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the salivary glands. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.
Gene Name: | carbonic anhydrase VII |
Synonyms: | CA7, Carbonic anhydrase VII, Carbonic dehydratase VII, CAVII, Carbonate dehydratase VII, Carbonic anhydrase 7, CA-VII |
Target Sequences: | NM_005182 NP_005173.1 P43166 |
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