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Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue.
Gene Name: | C1q and TNF Related 12 |
Synonyms: | C1QTNF12, Adipolin, C1QDC2, C1q/TNF-related protein 12, CTRP12, FAM132A, Protein FAM132A, C1q domain containing 2 |
Target Sequences: | NM_001014980 NP_001014980.1 Q5T7M4 |
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